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Phentermine vs Orlistat

Phentermine and Orlistat are two most popular drugs in the world that are used for reduction of extra weight and for the fight against obesity. These drugs can fight obesity very effectively, but each of them has different pharmacological effect on a patient’s body.

Orlistat overview

Orlistat is a drug, which doesn’t affect the appetite, but can be used for a long time, unlike Phentermine. Orlistat slows down or even blocks the action of enzymes that affect the fat absorption in the gastrointestinal tract (GIT). This allows the body excrete about 30% of fats consumed with food, in unchanged form.

Orlistat slimming pills were designated for an oral intake. Since 2007, low doses of Orlistat have been available at pharmacies of EU and USA without prescription (Alli). Orlistat 120 mg (Xenical) is only available by prescription.

Unlike Phentermine, Orlistat drug must be used before every food intake. If food contains a small amount of fat, you can skip the dose of Orlistat. It is not recommended to take over 3 pills of Orlistat 120 mg per day, since this measure doesn’t increase the effect of Orlistat drug.

Phentermine overview

Phentermine is an anorexigenic drug stimulating the brain and reducing the appetite. Phentermine has been used for obesity treatment since 1959. Today, it is the best-selling prescription drug for obesity treatment in the USA. People can buy Phentermine at the U.S. pharmacies by prescription only.

Phentermine slimming pills are meant for an oral use and cannot be used for more than 12 weeks. Patients should take Phentermine as 1 pill per day. Usually, this amount is enough to patient doesn’t feel hungry during a diet. It is recommended to take Phentermine in the morning; this allows to reduce the risk of such side effect as insomnia.

Phentermine and Orlistat side effects

Phentermine and Orlistat are potent slimming pills that help to get rid of obesity, but during their use side effect can appear. Phentermine may cause a significant impact on the CNS and cardiovascular system. Therefore, the most common side effects of Phentermine are:

  • Dyspnea or other breathing problems;
  • Emotional instability or uncertainty;
  • High blood pressure;
  • Change in heart rate;
  • Depression.

In addition, Phentermine slimming pills can cause some GIT side effects: dry mouth, uncontrolled or frequent defecation, nausea or vomiting.

Pharmacological effect of Orlistat slimming pills occurs in the GIT. Hence, the common side effects of Orlistat are associated with disorders of the GIT. Severe side effects of Orlistat depend on the amount of fat in food. These are:

  • Frequent and involuntary bowel movements;
  • Oily discharge from rectum;
  • Flatulence and bloating.

Apart from that, Orlistat can cause CNS side effects, for instance, violation of sleep cycles, headache and violation of spatial perception.

Summarizing everything said above, we can make a conclusion that there is no such thing as perfect remedy for obesity. Every drug has its pluses and minuses. Availability of many drugs for obesity treatment allows to choose an optimal variant for each patient individually.